Invitrogen™ SYT10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA570844

Product Code. 15849253

Description

This target displays homology in the following species: Cow: 79%; Dog: 86%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 86%.

SYT10 is a Ca2+ sensor specifically required for the Ca2+-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. SYT10 is not involved in Ca2+-dependent synaptic vesicle exocytosis. It acts through Ca2+ and phospholipid binding to the C2 domain: Ca2+ induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis.

Specifications

• Antigen: SYT10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SYT10
• Gene Alias: DKFZp781D2042; P65; SVP65; synaptotagmin 10; synaptotagmin X; Synaptotagmin-10; SYT; Syt10; SYT-10; SytX
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 341359
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q6XYQ8
• Gene Symbols: SYT10
• Immunogen: synthetic peptide directed towards the middle region of human SYT10.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG