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Invitrogen™ SYPL1 Recombinant Rabbit Monoclonal Antibody (K01_1Y98)
Description
Immunogen sequence: IKIATGHNII DELPPCKKKA VLCYFGSVTS MGSLNVSVIF GFLNMILWGG NAWFVYKETS LHSPSNTSAP HSQGGIPPPT GI Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 41%, Pig - 82%, Cynomolgus monkey - 94%.
The synaptophysin-like protein 1, also known as pantophysin, is a homolog of the neuroendocrine-specific protein synaptophysin, with the highest level of homology across its four transmembrane domains. Unlike synaptophysin however, SYPL1 is ubiquitously expressed and found in small cytoplasmic transport vesicles regardless of their content. SYPL1 is thought to play a multifunctional role in vesicle biogenesis and transport and is a component of adipocyte transport vesicles, and thus may be involved in adipocyte secretion. SYPL1 also interacts with vesicle-associated membrane protein 2 (VAMP-2) in adipocytes and associates with GLUT4-containing vesicles.
Specifications
Specifications
| Antigen | SYPL1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | K01_1Y98 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 150mM NaCl, 40% glycerol, 0.05% BSA and 0.01% sodium azide; pH 7.4 |
| Gene | SYPL1 |
| Gene Accession No. | Q16563 |
| Gene Alias | AI314763; AI604763; D12Ertd446e; H-SP1; Pan I; PanI; Pantophysin; Pphn; synaptophysin like 1; synaptophysin-like 1; synaptophysin-like protein; synaptophysin-like protein 1; SYPL; Sypl1 |
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