Invitrogen™ Synaptophysin Monoclonal Antibody (SP11)

Rabbit Monoclonal Antibody

Brand:  Invitrogen™ MA514532

Product Code. 11395083

Description

MA5-14532 targets Synaptophysin in IHC (P) and WB applications and shows reactivity with Human samples. The MA5-14532 immunogen is a synthetic peptide of human synaptophysin.

Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.

Specifications

• Antigen: Synaptophysin
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Tissue culture supernatant, TBS with 1% BSA and 0.1% sodium azide; pH 7.5
• Gene Accession No.: P07825, P08247, Q62277
• Gene Symbols: Syp
• Immunogen: A synthetic peptide of human synaptophysin (aa 250-313).
• Regulatory Status: RUO
• Gene ID (Entrez): 20977, 24804, 6855
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: SP11
• Conjugate: Unconjugated
• Gene: Syp
• Gene Alias: A230093K24Rik; AI848995; BM89 antigen; I79_012252; Major synaptic vesicle protein p38; MRX96; MRXSYP; p38; Syn; Synaptophysin; Syp; Syp I; Syp1
• Host Species: Rabbit
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG