Synapsin 1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA14673

Product Code. 15628038

Description

This antibody is specific for the ∽78 kDa Synapsin I protein doublet. Immunolabeling is blocked by preadsorption of the antibody with the protein used to generate the antibody. Reconstitute with 50 μL of PBS.

SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: Synapsin 1
• Classification: Polyclonal
• Gene: SYN1
• Gene Alias: Brain protein 4.1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20964, 24949, 281510, 6853
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: P17599, P17600, O88935, P09951
• Gene Symbols: SYN1
• Immunogen: Native protein purified from bovine brain
• Quantity: 10 μg
• Primary or Secondary: Primary
• Target Species: Bovine, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG