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Eurofins DiscoverX Syk Protein, Active
Description
SYK tyrosine kinase (spleen tyrosine kinase) is a key molecule in the development of the B cell lineage and the activation of B lymphocytes after Ag recognition by the B-cell receptor. Syk binds to ITAM motifs and initiates signaling pathway such as Ras, PI3 Kinase, Ca2+ flux , and PLCγ2. SYK is required for early B cell development.
GenBank L28824
Specifications
Specifications
| Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.0, 0.1 mM EGTA, 150 mM NaCl, 0.03% Brij-35, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol, 270 mM sucrose. Frozen solution. |
| Molecular Weight (g/mol) | 73 kDa |
| Quantity | 10 μg |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | N-terminal 6His |
| Expression System | Recombinant enzyme expressed in Sf21 insect cells |
| Protein Form | Full-length |
| Purity or Quality Grade | ≥62% |
| Protein | Syk, active |
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