Invitrogen™ SUZ12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA584345

Product Code. 16381295

Description

Immunogen sequence: NKPGSVKPTQ TIAVKESLTT DLQTRKEKDT PNENRQKLRI FYQFLYNNNT RQQTEARDDL HCPWCTLNCR KLYSLLKHLK LCHSRFIFNY VYHPKGARID VSINECYDGS YAGNPQDIHR QPGFAFSRNG PVKRTPIT Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 90%.

SUZ12 (polycomb protein SUZ12) is a zinc finger gene and has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. SUZ12 is also a component of the PRC2/EED-EZH2 complex which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3 leading to transcriptional repression of the affected target gene. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.

Specifications

• Antigen: SUZ12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SUZ12
• Gene Alias: 2610028O16Rik; AI195385; AU016842; AW536442; chET 9 protein; CHET9; chromatin precipitated E2F target 9 protein; D11Ertd530e; JJAZ1; Joined to JAZF1 protein; Kiaa0160; mKIAA0160; Polycomb protein Suz12; suppressor of zeste 12 homolog; suppressor of zeste 12 homolog (Drosophila); suppressor of zeste 12 protein homolog; Suz12; SUZ12 polycomb repressive complex 2 subunit
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23512
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q15022
• Gene Symbols: SUZ12
• Immunogen: Recombinant protein corresponding to Human SUZ12. Recombinant protein control fragment (Product #RP-102304).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG