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Invitrogen™ SUZ12 Monoclonal Antibody (3D10)
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Product Code. 11305703
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Quantity:
100 μL
Unit Size:
100µL
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11305703 100 μL 100µL
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Product Code. 11305703 Supplier Invitrogen™ Supplier No. MA515733

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Description

Mouse Monoclonal Antibody

MA5-15733 targets SUZ12 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples. The MA5-15733 immunogen is purified recombinant fragment of human SUZ12 expressed in E. Coli. MA5-15733 detects SUZ12 which has a predicted molecular weight of approximately 83.1kDa.

SUZ12 (polycomb protein SUZ12) is a zinc finger gene and has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. SUZ12 is also a component of the PRC2/EED-EZH2 complex which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3 leading to transcriptional repression of the affected target gene. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SUZ12
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 3D10
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene SUZ12
Gene Accession No. Q15022
Gene Alias 2610028O16Rik; AI195385; AU016842; AW536442; chET 9 protein; CHET9; chromatin precipitated E2F target 9 protein; D11Ertd530e; JJAZ1; Joined to JAZF1 protein; Kiaa0160; mKIAA0160; Polycomb protein Suz12; suppressor of zeste 12 homolog; suppressor of zeste 12 homolog (Drosophila); suppressor of zeste 12 protein homolog; Suz12; SUZ12 polycomb repressive complex 2 subunit
Gene Symbols SUZ12
Host Species Mouse
Immunogen Purified recombinant fragment of human SUZ12 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23512
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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