SUPV3L1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16870744	Proteintech 12826-1-AP-20UL	20 μL
16860744	Proteintech 12826-1-AP-150UL	150 μL

Description

SUV3, also known as SUPV3L1 (suppressor of var1, 3-like 1), is a 786 amino acid protein that localizes to both the nucleus and the mitochondrial matrix and contains one helicase C-terminal domain, as well as one helicase ATP-binding domain. Expressed in a broad range of tissues, SUV3 interacts with HBXIP and functions as an ATPase DNA/RNA helicase that uses magnesium as a cofactor to catalyze the unwinding of DNA/RNA and RNA/RNA duplexes, thereby playing a role in DNA replication and transcriptional initiation. SUV3 exhibits optimal activity at a pH of 5 and, in addition to its helicase activity, is thought to protect cells from apoptosis and participate in maintaining mitochondrial homeostasis.

Specifications

• Antigen: SUPV3L1
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, Immunoprecipitation
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Rat, Human
• Gene Accession No.: Q5EBA1, Q80YD1, Q8IYB8
• Gene ID (Entrez): 294385, 338359, 6832
• Immunogen: SUPV3L1 Fusion Protein Ag3542
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: SUPV3L1

• Concentration: 0.13 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: SUPV3L1, SUV3, SUV3 like protein 1
• Gene Symbols: Supv3l1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody