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Sunitinib, MedChemExpress

Product Code. 16481546
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Product Code. 16481546

Brand: Medchem Express HY10255A

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Description

MedChemExpress Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation.

Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation.

Specifications

Chemical Name or Material Sunitinib
CAS 557795-19-4
Color Yellow
Purity Grade Notes Research
Molecular Formula C22H27FN4O2
Quantity 500 mg
Synonym SU 11248
Solubility Information DMSO : 20.83 mg/mL (52.27 mM; ultrasonic and warming and heat to 80°C)
SMILES O=C(NCCN(CC)CC)C1=C(NC(/C=C2C(NC3=C\2C=C(C=C3)F)=O)=C1C)C
Molecular Weight (g/mol) 398.47
Formula Weight 398.47
Percent Purity 98.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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