Invitrogen™ SUMO2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA581548

Product Code. 16308564

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human SUMO2.

SUMO2 is a member of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.

Specifications

• Antigen: SUMO2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SUMO2
• Gene Alias: HSMT3; sentrin 2; sentrin-2; small ubiquitin-like modifier 2; small ubiquitin-like modifier 2 L homeolog; small ubiquitin-like modifier 3; small ubiquitin-related modifier 2; Small ubiquitin-related modifier 2-A; small ubiquitin-related modifier 3; SMT3 homolog 1; SMT3 homolog 2; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 2; SMT3 suppressor of mif two 3 homolog 2 (yeast); SMT3 suppressor of mif two 3 homolog 3; SMT3 supressor of mif two 3 homolog 2; Smt3A; Smt3b; SMT3H1; SMT3H2; Sumo2; SUMO-2; sumo2.L; SUMO-2-A; sumo2-a; sumo2-b; SUMO3; SUMO-3; Ubiquitin-like protein SMT3A; ubiquitin-like protein SMT3B; XELAEV_18044053mg
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 6613
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P61956
• Gene Symbols: SUMO2
• Immunogen: A synthetic peptide corresponding to the C-terminus of the Human SUMO2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG