Invitrogen™ SUMO-3 Recombinant Rabbit Monoclonal Antibody (1H9L17)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ 700186

Product Code. 15376944

Description

This antibody is predicted to react with chimpanzee and Rhesus monkey based on sequence homology. Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Small ubiquitin-related modifier proteins are members of the ubiquitin-like protein family. SUMO-3 regulates Amyloid beta generation and may be critical in the onset or progression of Alzheimer's disease. SUMO-2/3 forms poly-. SUMO-1, 2, and 3 proteins localize to the nuclear membrane, nuclear bodies, and cytoplasm, respectively. SUMOylation is essential for mammalian cell cycle regulation, SUMO-2/3 localizes to centromeres and condensed chromosomes where binds CENP-E.

Specifications

• Antigen: SUMO-3
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: P55854, Q5XIF4, Q9Z172
• Gene Symbols: SUMO3
• Immunogen: A peptide corresponding to amino acids 91-103 of P55854.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 1H9L17
• Conjugate: Unconjugated
• Gene: SUMO3
• Gene Alias: 2810014B19Rik; D10Ertd345e; small ubiquitin like modifier 3; small ubiquitin-like modifier 3; small ubiquitin-related modifier 3; SMT3 (supressor of mif two, 3) homolog 1; SMT3 homolog 1; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 3; SMT3 suppressor of mif two 3 homolog 3 (yeast); Smt3A; Smt3B; SMT3H1; SUMO-2; Sumo3; SUMO-3; Ubiquitin-like protein SMT3A; ubiquitin-like protein SMT3B
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 20610, 499417, 6612
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid