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Invitrogen™ Substance P Polyclonal Antibody
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Product Code. 16623325 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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16623325 100 μL 100µL
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Product Code. 16623325 Supplier Invitrogen™ Supplier No. PA5106886

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Substance P.

Substance P (SP) is currently thought to be one of the most important neurotransmitters and neurotransmitters in the brain. It is an undecapeptide belonging to the tachykinin family, which consists of excitatory neuropeptides synthesised in neuronal and glial cells of the human central and peripheral nervous system. Substance P, Neurokinin A, Neuropeptide K, and Neuropeptide gamma are all generated by post-translation cleavage of the precursor Protachykinin-1. Substance P forms the major endogenous ligand for Neurokinin 1 Receptor. The pharmacology of Substance P has been associated with a number of neurological and psychiatric disorders, namely nociception, migraine, asthma, nausea, inflammatory bowel syndrome, urinary incontinence, anxiety and depression. It has also been linked to obesity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Substance P
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TAC1
Gene Accession No. P06767, P20366, P41539
Gene Alias 4930528L02Rik; C-terminal-flanking peptide; Hs.2563; MGC26719; neurokinin 1; neurokinin 2; neurokinin A; neurokinin alpha; neuromedin L; Neuropeptide gamma; neuropeptide K; NK1; NK-1; NK2; Nka; Nkna; NPK; PPT; Ppt5fl; PPTA; PPT-A; PPTA3; precursor 1; preprotachykinin; preprotachykinin A; protachykinin; protachykinin-1; RAT TAC; RATPPTA3; SP; substance K; Substance P; TAC; Tac1; TAC2; Tachykinin (substance P, neurokinin A, neuropeptide K, neuropeptide gamma); tachykinin 1; tachykinin 2; tachykinin precursor 1; tachykinin, precursor 1; tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
Gene Symbols TAC1
Host Species Rabbit
Immunogen A synthesized peptide derived from human TAC1(Accession P20366), corresponding to amino acid residues L4-R54.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21333, 24806, 6863
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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