Invitrogen™ STOML1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA521557

Product Code. 13289088

Description

Recommended positive controls: Molt-4. Predicted reactivity: Mouse (84%), Rat (83%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Stomatin-like protein 1 (STOML1) is encoded by the STOML1 gene located on chromosome 17 in humans. It is part of a family of five mammalian genes that encode peripheral membrane proteins involved in modulating ion channel functions. STOML1 is known to interact specifically with members of the acid-sensing ion channel (ASIC) family, influencing their proton sensitivity. These interactions help regulate ion transport and signaling pathways, which are critical for cellular homeostasis. In addition, STOML1 has been studied in the context of oral squamous cell carcinoma (OSCC), where it is often overexpressed along with STOML2, potentially affecting cancer progression. Structurally, STOML1 contains a stomatin domain which is crucial for its role in membrane association and ion channel modulation. Its expression in olfactory sensory neurons (OSNs) is comparatively lower than other family members, but it still contributes to the localization and functional integrity of related proteins in these cells.

Specifications

• Antigen: STOML1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: STOML1
• Gene Alias: 1810015E19Rik; AI847431; EPB72-like 1; EPB72-like protein 1; hUNC-24; MSTP019; Protein unc-24 homolog; RGD1559463; SLP1; SLP-1; stomatin (EBP72)-like 1; stomatin (EPB72)-like 1; stomatin like 1; stomatin-like 1; stomatin-like protein 1; Stomatin-related protein; STOML1; STORP; UNC24; WPB72
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9399
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9UBI4
• Gene Symbols: STOML1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human STOML1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG