STK17B Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16805025	Proteintech 26600-1-AP-20UL	20 μL
16895015	Proteintech 26600-1-AP-150UL	150 μL

Description

Protein kinases play important roles in the signal transduction in response to a variety of external stimuli. Recently, several protein kinases have been identified that may also be involved in apoptotic process. Overexpression of a serine/threonine kinase, ZIP kinase can cause the morphological changes typical of apoptosis in NIH 3T3 cells. Sanjo et al, have identified two new protein kinases DRAK1 and DRAK2 (Death Receptor Associated Kinase 1 and 2). Both DRAKs and ZIP kinase share significant homology at the amino acid level. The kinase domains of both DRAKs, ZIP kinase are homologous to DAP (Death-associated protein) kinase, which is involved in the apoptotic signaling induced by interferon-g. Overexpression of DRAKs in NIH 3T3 cells lead to apoptosis. These transfection experiments suggest that C-terminal domain of DRAKs are important for induction of apoptosis.

Specifications

• Antigen: STK17B
• Applications: Western Blot, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: O94768
• Gene ID (Entrez): 9262
• Immunogen: STK17B Fusion Protein Ag24389
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: STK17B

• Concentration: 0.33 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: DRAK2, serine/threonine kinase 17b, STK17B
• Gene Symbols: STK17B
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody