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Invitrogen™ STEAP3 Polyclonal Antibody

Product Code. 12828592
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Quantity:
100 μg
Unit Size:
100µg
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12828592 100 μg 100µg
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Product Code. 12828592 Supplier Invitrogen™ Supplier No. PA520406

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Description

Rabbit Polyclonal Antibody

A suggested positive control is rat liver tissue lysate. PA5-20406 can be used with blocking peptide PEP-0523.

The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STEAP3
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene STEAP3
Gene Accession No. Q5RKL5, Q658P3, Q8CI59
Gene Alias 1010001D01Rik; AHMIO2; dudlin 2; dudlin-2; dudulin 2; dudulin-2; hpHyde; hTSAP6; Metalloreductase STEAP3; pHyde; Protein nm1054; six-transmembrane epithelial antigen of prostate 3; STEAP family member 3; STEAP family member 3, metalloreductase; STEAP3; STEAP3 metalloreductase; STMP3; TSAP6; tumor suppressor pHyde; tumor suppressor-activated pathway protein 6
Gene Symbols STEAP3
Host Species Rabbit
Immunogen A 15 amino acid peptide from near the amino terminus of human STEAP3.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 170824, 55240, 68428
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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