Invitrogen™ Staufen Monoclonal Antibody (K16281_1A8), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA556031

Product Code. 30207302

Description

Sequence of this protein is as follows: LNKSEISQVF EIALKRNLPV NFEVARESGP PHMKNFVTKV SVGEFVGEGE GKSKKISKKN AAIAVLEELK KLPPLPAVER VKPRIKKKTK PIVKPQTSPE YGQGINPISR LAQIQQAKKE KEPEYTLLTE RGLPRRREFV MQVKVGNHTA EGTGTNKKVA KRNAAENMLE ILGFKVPQAQ

STAU1 is a member of a family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human STAU1 also contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. STAU1 has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER. STAU1 is also known to interact with influenza ribonucleoproteins NS1, NP, and PA and is required for efficient viral replication.

Specifications

• Antigen: Staufen
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
• Gene Accession No.: O95793
• Gene Symbols: Stau1
• Immunogen: Recombinant human STAU1 (immunogen range is 181-360).
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: K16281_1A8
• Conjugate: Unconjugated
• Gene: Stau1
• Gene Alias: 5830401L18Rik; AW549911; C85792; Double-stranded RNA-binding protein Staufen homolog 1; PPP1R150; protein phosphatase 1, regulatory subunit 150; RP3-470L14.2; STAU; Stau1; staufen (RNA binding protein) homolog 1 (Drosophila); staufen double-stranded RNA binding protein 1; staufen RNA binding protein homolog 1; staufen, RNA binding protein, homolog 1
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 6780, 84496
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid