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StAR Antibody (STAR/2154) - Azide and BSA Free, Novus Biologicals™

Product Code. 18363311 Shop All Bio Techne Products
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Quantity:
100 μg
Unit Size:
100µg
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18363311 100 μg 100µg
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Product Code. 18363311 Supplier Novus Biologicals Supplier No. NBP275742

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Description

Mouse Monoclonal Antibody

StAR Monoclonal specifically detects StAR in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.
TRUSTED_SUSTAINABILITY

Specifications

Antigen StAR
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone STAR/2154
Concentration 0.2 mg/ml
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin 1-2 ug/ml
Formulation 10 mM PBS with No Preservative
Gene Alias cholesterol trafficker, mitochondrial steroid acute regulatory protein, StAR, StARD1, STARD1StAR-related lipid transfer (START) domain containing 1, START domain containing 1, START domain-containing protein 1, steroid acute regulatory protein, steroidogenic acute regulator, steroidogenic acute regulatory protein, steroidogenic acute regulatory protein, mitochondrial
Gene Symbols STAR
Host Species Mouse
Immunogen Recombinant fragment (around aa 39-108) of human StAR protein (exact sequence is proprietary) (Uniprot: P49675)
Molecular Weight of Antigen 30 kDa
Purification Method Protein A or G purified
Quantity 100 μg
Research Discipline Cancer
Primary or Secondary Primary
Gene ID (Entrez) 6770.0
Test Specificity Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.
Target Species Human
Content And Storage Store at 4°C.
Form Purified
Isotype IgG1 κ
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