Invitrogen™ STAM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA583276

Product Code. 16350235

Description

Immunogen sequence: EAPVYSVYSK LHPPAHYPPA SSGVPMQTYP VQSHGGNYMG QSIHQVTVAQ SYSLGPDQIG PLRSLPPNVN SSVTA Highest antigen sequence indentity to the following orthologs: Rat - 73%, Mouse - 80%.

The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.

Specifications

• Antigen: STAM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: STAM2
• Gene Alias: 1200004O12Rik; 5730456G07Rik; BB145015; DKFZp564C047; Hbp; HGNC:11358; Hrs binding protein; hrs-binding protein; HSE1 homolog; signal transducing adapter molecule 2; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2; signal transducing adaptor molecule 2; STAM2; STAM-2; STAM2A; STAM2B; STAM-like protein containing SH3 and ITAM domains 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10254
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O75886
• Gene Symbols: STAM2
• Immunogen: Recombinant protein corresponding to Human STAM2. Recombinant protein control fragment (Product #RP-96005).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG