Invitrogen™ SSX2 Monoclonal Antibody (CL3202)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA524652

Product Code. 15779300

Description

Immunogen sequence: GKHAWTHRLR ERKQLVIYEE ISDPEEDDE Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 79%. Binds to an epitope located within the peptide sequence GKHAWTHRLRERKQL as determined by overlapping synthetic peptides.

SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Specifications

• Antigen: SSX2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q16385
• Gene Symbols: Ssx2
• Immunogen: Recombinant protein corresponding to Human SSX2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin)
• Clone: CL3202
• Conjugate: Unconjugated
• Gene: Ssx2
• Gene Alias: cancer/testis antigen 5.2; cancer/testis antigen family 5, member 2a; CT5.2; CT5.2A; CT52; HD21; HOM-MEL-40; LOC103690782; MGC119055; MGC15364; MGC3884; Protein SSX2; putative protein SSX10; sarcoma, synovial, X-chromosome-related 2; SSX; SSX family member 2; SSX2; SSX2A; SSX2B; Synovial sarcoma, X breakpoint 2; synovial sarcoma, X breakpoint 2B; tumor antigen HOM-MEL-40
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 6757
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid