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  8. SSR 146977 hydrochloride, Tocris Bioscience™

SSR 146977 hydrochloride, Tocris Bioscience™

Catalog Number 18095292
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Quantity:
10 mg
50 mg
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264618-38-4
C35H43Cl3N4O2
658.105
HYPKKQPFHSNZBY-GXUZKUJRSA-N
ssr 146977 hydrochloride, ssr 146977 hydrochloride/ssr-146977, n1-1-3-3r-1-benzoyl-3-3-3,4-dichlorophenyl-3-piperidinyl propyl-4-phenyl-piperidinyl-n,n-dimethylurea hydrochloride
90488827
3-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-1,1-dimethylurea;hydrochloride
CN(C)C(=O)NC1(CCN(CC1)CCCC2(CCCN(C2)C(=O)C3=CC=CC=C3)C4=CC(=C(C=C4)Cl)Cl)C5=CC=CC=C5.Cl
This item is not returnable. View return policy
264618-38-4
C35H43Cl3N4O2
658.105
HYPKKQPFHSNZBY-GXUZKUJRSA-N
ssr 146977 hydrochloride, ssr 146977 hydrochloride/ssr-146977, n1-1-3-3r-1-benzoyl-3-3-3,4-dichlorophenyl-3-piperidinyl propyl-4-phenyl-piperidinyl-n,n-dimethylurea hydrochloride
90488827
3-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-1,1-dimethylurea;hydrochloride
CN(C)C(=O)NC1(CCN(CC1)CCCC2(CCCN(C2)C(=O)C3=CC=CC=C3)C4=CC(=C(C=C4)Cl)Cl)C5=CC=CC=C5.Cl

Description

Potent and selective NK3 antagonist

Potent and selective NK3 receptor antagonist (Ki values are 0.26 and 19.3 nM in CHO cells expressing the human NK3 and NK2 receptor respectively). Also inhibits senktide -induced inositol monophosphate formation and intracellular calcium mobilization (IC50 = 10 nM).
Quantity 50 mg
Formula Weight 658.11
Percent Purity >98%
Chemical Name or Material SSR 146977 hydrochloride
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