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Invitrogen™ SSEA3 Monoclonal Antibody (MC-631)
Description
SSEA3 Monoclonal Antibody for Flow, ICC/IF
SSEA-3 (stage-specific embryonic antigen 3) is a cell surface antigen, expressed along with SSEA-4, TRA-1-60 and TRA-1-81 in embryonic stem cells, embryonal carcinoma cells, and induced pluripotent stem cells (iPS). In human cells, these surface markers are down-regulated during the differentiation process, while SSEA1 is absent in undifferentiated human stem cells and upregulated on the cell surface after retinoic acid mediated differentiation. Conversely, in mouse stem cells, SSEA-1 expression decreases with differentiation while SSEA-3 and SSEA-4 expression increase.
Specifications
Specifications
| Antigen | SSEA3 |
| Applications | Flow Cytometry, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | MC-631 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | Potassium phosphate with 0.15M NaCl, 1mg/mL BSA and 0.05% sodium azide |
| Gene Alias | SSEA-3; stage-specific embryonic antigen 3 |
| Host Species | Rat |
| Immunogen | Fischer rat immunized with 4-8 cell stage mouse embryos. |
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