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Invitrogen™ SRY Monoclonal Antibody (1G4)
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Product Code. 15388140
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Quantity:
100 μg
Unit Size:
100µg
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15388140 100 μg 100µg
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Product Code. 15388140 Supplier Invitrogen™ Supplier No. MA517181

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Description

Mouse Monoclonal Antibody

MA5-17181 targets SRY in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human samples. The MA5-17181 immunogen is purified recombinant fragment of human SRY (amino acids:1-204) expressed in E. Coli. MA5-17181 detects SRY which has a predicted molecular weight of approximately 23.9kDa.

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SRY
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1G4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene SRY
Gene Accession No. Q05066
Gene Alias essential protein for sex determination in human males; HMG box transcription factor Sry1; HMG box transcription factor Sry3BI; sex determining region of Chr Y; sex determining region on Y; sex determining region Y; sex determining region Y protein; sex-determining region on Y; sex-determining region Y protein; SRXX1; SRXY1; Sry; Sry1; Sry3BI; SRYGENE; TDF; TDY; Testis determining locus; testis determining-Y; testis-determining factor; testis-determining factor on Y
Gene Symbols SRY
Host Species Mouse
Immunogen Purified recombinant fragment of human SRY (amino acids:1-204) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6736
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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