Invitrogen™ SRSF2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA578164

Product Code. 16306874

Description

Positive Control: HL-60 Predicted Reactivity: Rat (100%), Pig (100%), Chicken (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by SC35 is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for SC35. In addition, a pseudogene of SC35 has been found on chromosome 11.

Specifications

• Antigen: SRSF2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SRSF2
• Gene Alias: D11Wsu175e; MRF-1; myelin regulatory factor 1; Pr264; Protein PR264; Putative myelin regulatory factor 1; SC35; SC-35; serine and arginine rich splicing factor 2; serine/arginine-rich splicing factor 2; Sfrs10; Sfrs2; SFRS2A; splicing component, 35 kDa; Splicing factor SC35; splicing factor, arginine/serine-rich 2; splicing factor, arginine/serine-rich 2 (SC-35); SR splicing factor 2; SRp30b; Srsf2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20382, 6427
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.65 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q01130, Q62093
• Gene Symbols: SRSF2
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SC35. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG