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Invitrogen™ SRSF2 Polyclonal Antibody

Product Code. 16306874
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Quantity:
100 μL
Unit Size:
100µL
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16306874 100 μL 100µL
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Product Code. 16306874 Supplier Invitrogen™ Supplier No. PA578164

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Description

Rabbit Polyclonal Antibody

Positive Control: HL-60 Predicted Reactivity: Rat (100%), Pig (100%), Chicken (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by SC35 is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for SC35. In addition, a pseudogene of SC35 has been found on chromosome 11.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SRSF2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.65 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene SRSF2
Gene Accession No. Q01130, Q62093
Gene Alias D11Wsu175e; MRF-1; myelin regulatory factor 1; Pr264; Protein PR264; Putative myelin regulatory factor 1; SC35; SC-35; serine and arginine rich splicing factor 2; serine/arginine-rich splicing factor 2; Sfrs10; Sfrs2; SFRS2A; splicing component, 35 kDa; Splicing factor SC35; splicing factor, arginine/serine-rich 2; splicing factor, arginine/serine-rich 2 (SC-35); SR splicing factor 2; SRp30b; Srsf2
Gene Symbols SRSF2
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SC35. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20382, 6427
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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