Invitrogen™ SRSF11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA552606

Product Code. 15700561

Description

Immunogen sequence: LLPTPNPLTQ IGAVPLAALG APTLDPALAA LGLPGANLNS QSLAADQLLK LMSTVDPKLN HVAAGLVSPS LKSDTSSKEI EEAMKRVREA QSLISAAIEP DKKEEKRRHS RSRSR Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Pre-mRNA splicing enhancer elements are short RNA sequences capable of activating weak splice sites in nearby introns that are required for accurate splice site recognition and the control of alternative splicing. Splicing enhancer elements contain specific binding sites for serine/arginine (SR)-rich splicing factors, which include SC35, 9G8, SRp20 and SF2/ASF. The family of SR factors all contain one or more RNA recognition motifs (RRM) and a SR-rich domain. The SR factor family is not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. SFRS11 (splicing factor, arginine/serine-rich 11), also known as arginine-rich 54 kDa nuclear protein (p54) or NET2, is a 484 amino acid nuclear protein that colocalizes with spliceosome components and belongs to the splicing factor SR family. SFRS11 may function in pre-mRNA splicing and contains one RRM (RNA recognition motif) domain.

Specifications

• Antigen: SRSF11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SRSF11
• Gene Alias: 0610009J05Rik; 2610019N13Rik; Arginine-rich 54 kDa nuclear protein; BF642805; dJ677H15.2; NET2; p54; serine and arginine rich splicing factor 11; serine/arginine-rich splicing factor 11; SFR11; Sfrs11; splicing factor p54; splicing factor, arginine/serine-rich 11; SR splicing factor 11; Srsf11
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9295
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q05519
• Gene Symbols: SRSF11
• Immunogen: Recombinant protein corresponding to Human SRSF11. Recombinant protein control fragment (Product #RP-88824).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG