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SR12813, MedChemExpress

Product Code. 16493168
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Product Code. 16493168 Supplier Medchem Express Supplier No. HY100793

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Description

MedChemExpress SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM. SR12813 is also an efficient agonist of human pregnane X receptor (hPXR). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR).

SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM. SR12813 is also an efficient agonist of human pregnane X receptor (hPXR). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR).

Specifications

Chemical Name or Material SR12813
CAS 126411-39-0
Color White
Purity Grade Notes Research
Molecular Formula C24H42O7P2
Quantity 10 mg
Synonym GW 485801
Solubility Information DMSO : ≥ 50 mg/mL (99.10 mM)
SMILES OC1=C(C(C)(C)C)C=C(/C=C(P(OCC)(OCC)=O)/P(OCC)(OCC)=O)C=C1C(C)(C)C
Molecular Weight (g/mol) 504.53
Formula Weight 504.53
Percent Purity 99.39%
Grade Research
Physical Form Solid
For Use With (Application) Metabolism-sugar/lipid metabolism
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Research purposes only

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