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SR 202, Tocris Bioscience™

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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Description
Selective PPARγ antagonist; antidiabetic and antiobesity agent. Attenuates troglitazone-induced PPARγ transcriptional activity (IC50 = 140 μM) without affecting ligand-stimulated PPARα, PPARβ or FXR transcriptional activity. Inhibits PPARγ-dependent adipocyte differentiation and growth in vitro and in vivo. Improves insulin sensitivity in diabetic ob/ob mice and increases HDL levels in rats in vivo.
Specifications
Specifications
| Quantity | 10 mg |
| Formula Weight | 358.65 |
| Percent Purity | >99% |
| Chemical Name or Material | SR 202 |
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