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SR 142948, Tocris Bioscience™
Highly potent NTS receptor antagonist
£149.02 - £273.35
Chemical Identifiers
| CAS | 184162-64-9 |
|---|---|
| Molecular Formula | C39H51N5O6 |
| Molecular Weight (g/mol) | 685.866 |
| InChI Key | LWULHXVBLMWCHO-UHFFFAOYSA-N |
| Synonym | d0oj7s, sr 142948 hydrochloride, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylamino propyl methylamino carbonyl-2-1-methylethyl phenyl-1h-pyrazol-3-yl carbonyl amino-tricyclo 3.3.1.13,7 decane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-n-3-dimethylaminopropyl-n-methylcarbamoyl-2-isopropylphenyl-1h-pyrazole3-carbonyl amino adamantane-2-carboxylic acid hydrochloride, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylaminopropyl-methylcarbamoyl-2-propan-2-ylphenyl pyrazole-3-carbonyl amino adamantane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylamino propyl-methylcarbamoyl-2-propan-2-ylphenyl pyrazole-3-carbonyl amino adamantane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylamino propyl methyl carbamoyl-2-isopropylphenyl pyrazole-3-amido adamantane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-n-methyl-n-3-dimethylaminopropyl carbamoyl-2-isopropylphenyl-3-pyrazolylcarbonylamino-2-adamantanecarboxylic acid |
| PubChem CID | 5311451 |
| IUPAC Name | 2-[[5-(2,6-dimethoxyphenyl)-1-[4-[3-(dimethylamino)propyl-methylcarbamoyl]-2-propan-2-ylphenyl]pyrazole-3-carbonyl]amino]adamantane-2-carboxylic acid |
| SMILES | CC(C)C1=C(C=CC(=C1)C(=O)N(C)CCCN(C)C)N2C(=CC(=N2)C(=O)NC3(C4CC5CC(C4)CC3C5)C(=O)O)C6=C(C=CC=C6OC)OC |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
30001411
|
Tocris Bioscience
2309/1 |
1 mg |
£149.02
1mg |
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|
18073792
|
Tocris Bioscience
2309/10 |
10 mg |
£273.35
10mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Potent non-peptide neurotensin (NT) receptor antagonist that binds with high affinity (IC50 = 0.32 - 3.96 nM; Ki < 10 nM). Attenuates amphetamine-induced hyperactivity and is orally active in vivo.Chemical Identifiers
| 184162-64-9 | |
| 685.866 | |
| d0oj7s, sr 142948 hydrochloride, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylamino propyl methylamino carbonyl-2-1-methylethyl phenyl-1h-pyrazol-3-yl carbonyl amino-tricyclo 3.3.1.13,7 decane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-n-3-dimethylaminopropyl-n-methylcarbamoyl-2-isopropylphenyl-1h-pyrazole3-carbonyl amino adamantane-2-carboxylic acid hydrochloride, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylaminopropyl-methylcarbamoyl-2-propan-2-ylphenyl pyrazole-3-carbonyl amino adamantane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylamino propyl-methylcarbamoyl-2-propan-2-ylphenyl pyrazole-3-carbonyl amino adamantane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylamino propyl methyl carbamoyl-2-isopropylphenyl pyrazole-3-amido adamantane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-n-methyl-n-3-dimethylaminopropyl carbamoyl-2-isopropylphenyl-3-pyrazolylcarbonylamino-2-adamantanecarboxylic acid | |
| 2-[[5-(2,6-dimethoxyphenyl)-1-[4-[3-(dimethylamino)propyl-methylcarbamoyl]-2-propan-2-ylphenyl]pyrazole-3-carbonyl]amino]adamantane-2-carboxylic acid |
| C39H51N5O6 | |
| LWULHXVBLMWCHO-UHFFFAOYSA-N | |
| 5311451 | |
| CC(C)C1=C(C=CC(=C1)C(=O)N(C)CCCN(C)C)N2C(=CC(=N2)C(=O)NC3(C4CC5CC(C4)CC3C5)C(=O)O)C6=C(C=CC=C6OC)OC |
Specifications
| 184162-64-9 | |
| d0oj7s, sr 142948 hydrochloride, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylamino propyl methylamino carbonyl-2-1-methylethyl phenyl-1h-pyrazol-3-yl carbonyl amino-tricyclo 3.3.1.13,7 decane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-n-3-dimethylaminopropyl-n-methylcarbamoyl-2-isopropylphenyl-1h-pyrazole3-carbonyl amino adamantane-2-carboxylic acid hydrochloride, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylaminopropyl-methylcarbamoyl-2-propan-2-ylphenyl pyrazole-3-carbonyl amino adamantane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylamino propyl-methylcarbamoyl-2-propan-2-ylphenyl pyrazole-3-carbonyl amino adamantane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylamino propyl methyl carbamoyl-2-isopropylphenyl pyrazole-3-amido adamantane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-n-methyl-n-3-dimethylaminopropyl carbamoyl-2-isopropylphenyl-3-pyrazolylcarbonylamino-2-adamantanecarboxylic acid | |
| CC(C)C1=C(C=CC(=C1)C(=O)N(C)CCCN(C)C)N2C(=CC(=N2)C(=O)NC3(C4CC5CC(C4)CC3C5)C(=O)O)C6=C(C=CC=C6OC)OC | |
| 685.866 | |
| 685.86 | |
| SR 142948 |
| C39H51N5O6 | |
| LWULHXVBLMWCHO-UHFFFAOYSA-N | |
| 2-[[5-(2,6-dimethoxyphenyl)-1-[4-[3-(dimethylamino)propyl-methylcarbamoyl]-2-propan-2-ylphenyl]pyrazole-3-carbonyl]amino]adamantane-2-carboxylic acid | |
| 5311451 | |
| >97% |
Safety and Handling
Recommended Storage : Store at +4°C