Invitrogen™ SQRDL Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA553549

Product Code. 15701491

Description

Immunogen sequence: TSPVADAAGW VDVDKETLQH RRYPNVFGIG DCTNLPTSKT AAAVAAQSGI LDRTISVIMK NQTPTKKYDG YTSCPLVTGY NRVILAEFDY KAEPLETFPF DQSKERLSMY LMKADLMPFL YWNMMLRGYW G Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 93%.

SQRDL (Sulfide: quinone oxidoreductase, mitochondrial) catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. Although the SQRDL precursor protein displays a molecular weight of 50 kDa, a prominent band at about 46 kDa is detected by western blot. This discrepancy reflects the cleavage of an N-terminal targeting sequence of 4 kDa during the import of the protein into the mitochondria. SQRDL is one of the enzymes involved in H2S signaling in a discrete population of neurons, oligodendrocytes, and endothelial cells.

Specifications

• Antigen: SQRDL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Sqor
• Gene Alias: 0610039J17Rik; 4930557M22Rik; Cc2-17; CGI-44; flavo-binding protein; PRO1975; SQOR; Sqrdl; sulfide dehydrogenase like; Sulfide dehydrogenase-like; Sulfide quinone oxidoreductase; sulfide quinone reductase-like (yeast); sulfide:quinone oxidoreductase, mitochondrial
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 58472, 59010
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.30 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9R112, Q9Y6N5
• Gene Symbols: Sqor
• Immunogen: Recombinant protein corresponding to Human SQRDL. Recombinant protein control fragment (Product #RP-89842).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG