Invitrogen™ SPZ1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5103354

Product Code. 16659804

Description

Antibody detects endogenous levels of total SPZ1.

Spermatogenic leucine zipper protein 1 is a member of the basic helix-loop-helix (bHLH) family of transcription factors which is expressed specifically in the testis and epididymis. Studies show that SPZ1 acts downstream of mitogen-activated protein kinase (MAPK), an extracellular signal-regulated kinase 1/2 to up-regulate cell proliferation and tumorigenesis. Also, through an interaction with proliferating cell nuclear antigen (PCNA) promoter, SPZ1 induced cell proliferation concomitant with an increase in PCNA gene expression.

Specifications

• Antigen: SPZ1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Spz1
• Gene Alias: 1700027M20Rik; AI429130; bhlh-zip transcription factor SPZ1; NYD-TSP1; PPP1R148; protein phosphatase 1, regulatory subunit 148; spermatogenic leucine zipper 1; spermatogenic leucine zipper protein 1; Spermatogenic Zip 1; SPZ1; testis secretory sperm-binding protein Li 232m; testis-specific protein 1; Testis-specific protein NYD-TSP1; TSP1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 499510, 84654
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q6AXY9, Q9BXG8
• Gene Symbols: Spz1
• Immunogen: A synthesized peptide derived from human SPZ1(Accession Q9BXG8), corresponding to amino acid residues E111-I161.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG