Invitrogen™ SPINLW1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA596071

Product Code. 16558911

Description

Immunogen sequence: PGLTDWLFPR RCPKIREECE FQERDVCTKD RQCQDNKKCC VFSCGKKCLD LKQDVCEMPK ETGPCLAYFL HWWYDKKDNT CSMFVYGGCQ GNNNNFQSKA NCLNTCKNKR FP; Positive Samples: Mouse testis; Cellular Location: Cell surface.

Eppin, an epididymal protease inhibitor, belongs to the WFDC family and to the telomeric cluster. The gene encoding the protein is localized to chromosome 20q12-q13 in centromeric and telomeric clusters. It expresses three mRNAs encoding two isoforms of a cystine-rich protein that contains Kunitz-type and WAP-type (four disulfide core) protease inhibitor consensus sequences. The mouse gene lies in a cluster of putative Eppin-like genes on mouse chromosome 2. Following ejaculation, Eppin is bound to semenogelin in seminal plasma and on human spermatozoa. This complex of Eppin and Semenogelin can provide antimicrobial activity for spermatozoa. It can also provide for the preparation and survival of spermatozoa for fertility in the female reproductive tract. Eppin, which is a secreted protein, is expressed in epididymis and testis.

Specifications

• Antigen: SPINLW1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPPIN
• Gene Alias: 1700024E17Rik; cancer/testis antigen 71; cancer/testis antigen 72; CT71; CT72; dJ461P17.2; epididymal peptidase inhibitor; epididymal protease inhibitor; EPPIN; EPPIN1; EPPIN2; EPPIN3; protease inhibitor WAP7; serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin); serine protease inhibitor-like with Kunitz and WAP domains 1; serine protease inhibitor-like, with Kunitz and WAP domains 1 (eppin); Spinlw1; WAP four-disulfide core domain protein 7; WAP four-disulfide core domain protein 8; WAP7; WFDC7; Wfdc8
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57119, 685161, 75526
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.93 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: D4A2Z2, O95925, Q9DA01
• Gene Symbols: EPPIN
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-133 of human EPPIN (NP_0651311).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG