Invitrogen™ SPINK7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA551287

Product Code. 15685205

Description

The antibody detects endogenous levels of total SPINK7 protein.

SPINK7 (serine peptidase inhibitor, Kazal type 7), also known as Ecg2 (esophagus cancer-related gene 2 protein), is a 76 amino acid secreted protein. Containing one Kazal-like domain, SPINK7 is thought to be a serine protease inhibitor. The gene that encodes SPINK7 maps to human chromosome 5, which contains 181 million base pairs encoding around 1,000 genes. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.Probable serine protease inhibitor.

Specifications

• Antigen: SPINK7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPINK7
• Gene Alias: ECG2; ECRG2; ECRG-2; EG408198; esophagus cancer related gene 2; esophagus cancer-related gene 2 protein; esophagus cancer-related gene-2; esophagus cancer-related protein 2; serine peptidase inhibitor, Kazal type 7; serine peptidase inhibitor, Kazal type 7 (putative); serine protease inhibitor Kazal-type 7; SPINK7; UNQ745/PRO1474
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84651
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P58062
• Gene Symbols: SPINK7
• Immunogen: Synthetic peptide of human SPINK7.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG