Invitrogen™ SPIN1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA584790

Product Code. 16301745

Description

Immunogen sequence: MKTPFGKTPG QRSRADAGHA GVSANMMKKR TSHKKHRSSV GPSKPVSQPR RNI Highest antigen sequence indentity to the following orthologs: Rat - 98%, Mouse - 98%.

SPIN1 (spindlin 1), also known as SPIN or ovarian cancer-related protein (OCR), is a 262 amino acid nuclear protein suggested to play a role in regulation of the cell-cycle during the transition from gamete to embryo. A member of the SPIN/STSY family, SPIN1 localizes to interphase nucleus and mitotic chromosomes, and is modified by phosphorylation in a cell-cycle-dependent fashion. A meiotic spindle-binding protein, SPIN1 overexpression has been shown to cause defects in mitotic spindles, thereby resulting in chromosome instability and potential tumorigenesis.

Specifications

• Antigen: SPIN1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPIN1
• Gene Alias: 30000 Mr metaphase complex; OCR; Ovarian cancer-related protein; SPIN; Spin1; spindlin 1; Spindlin1; spindlin-1; SSEC P; TDRD24
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10927
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y657
• Gene Symbols: SPIN1
• Immunogen: Recombinant protein corresponding to Human SPIN1. Recombinant protein control fragment (Product #RP-107652).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG