Invitrogen™ SPG21 Monoclonal Antibody (2B11)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA521907

Product Code. 15539052

Description

Peptide Sequence: PHKIRDIPVT IMDVFDQSAL STEAKEEMYK LYPNARRAHL KTGGNFPYLC RSAEVNLYVQ IHLLQFHGTK YAAIDPSMVS AEELEVQKGS LGISQE.

The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.

Specifications

• Antigen: SPG21
• Classification: Monoclonal
• Concentration: 0.2-1.0 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q9NZD8
• Gene Symbols: SPG21
• Immunogen: SPG21 (NP_057714, 211 a.a. ~ 306 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA
• Clone: 2B11
• Conjugate: Unconjugated
• Gene: SPG21
• Gene Alias: acid cluster protein 33; ACP33; BM-019; C78576; D9Wsu18e; GL010; Maspardin; MAST; spastic paraplegia 21 (autosomal recessive, Mast syndrome); Spastic paraplegia 21 autosomal recessive Mast syndrome protein; Spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog; spastic paraplegia 21 homolog (human); Spastic paraplegia 21 protein; SPG21
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51324
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid