missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. SPDEF Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

SPDEF Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16898563 Shop All Proteintech Products
Change view
Click to view available options
Quantity:
20 μL
150 μL
Unit Size:
150µL
20µL
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
16898563 20 μL 20µL
16888563 150 μL 150µL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Product Code. 16898563 Supplier Proteintech Supplier No. 114671AP20UL

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Rabbit Polyclonal Antibody

PDEF (prostate-derived Ets factor) is a 37.5- kDa protein that acts as an androgen-independent transcriptional activator for the PSA (prostate specific antigen) promoter. It also interacts directly with the DNA binding domain of androgen receptor and enhances androgen-mediated activation of the PSA promoter. PDEF was shown to have transcript levels 192-fold higher in the peripheral blood of some breast cancer patients in comparison with normal individuals. PDEF mRNA is also frequently over-expressed in human breast tumors as well as in human ovarian tumors. In ovarian tumors, PDEF expression seems to down-modulate maligt potential, and thus provides a rationale to screen for drugs that induce PDEF expression in epithelial ovarian tumors.

Specifications

Antigen SPDEF
Applications Western Blot
Classification Polyclonal
Concentration 0.31 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene SPDEF
Gene Accession No. O95238, Q9WTP3
Gene Alias PDEF, Prostate derived Ets factor, Prostate specific Ets, PSE, RP11 375E1__A.3, SPDEF
Gene Symbols SPDEF
Host Species Rabbit
Immunogen SPDEF Fusion Protein Ag2020
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25803, 30051, 689210
Target Species Mouse, Rat, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.