Invitrogen™ SPANXC Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA583819

Product Code. 16330775

Description

Immunogen sequence: SDPQPAPKKL KTSESSTILV VRYRRN Highest antigen sequence indentity to the following orthologs: Mouse - 42%, Rat - 42%.

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy.

Specifications

• Antigen: SPANXC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPANXC
• Gene Alias: C; cancer/testis antigen 11.3; cancer/testis antigen family 11, member 3; cancer/testis-associated protein CTp11; cancer/testis-associated protein of 11 kD; cancer-testis-associated protein CTp11; CT11.3; CTp11; nuclear-associated protein SPAN-Xc; SPANX family member C; SPANX family, member C; SPANXC; SPANX-C; SPAN-Xc protein; Sperm protein associated with the nucleus on the X chromosome C; sperm protein associated with the nucleus, X chromosome, family member C
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64663
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NY87
• Gene Symbols: SPANXC
• Immunogen: Recombinant protein corresponding to Human SPANXC. Recombinant protein control fragment (Product #RP-99048).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG