Invitrogen™ SPAK Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5115976

Product Code. 17288753

Description

Antibody detects endogenous levels of total STK39.

STK39 (STLK3) is involved in the cellular stress response pathway. STK39 is activated in response to hypotonic stress leading to phosphorylation of several cation-chloride-coupled co-transporters. STK39 activates the p38 MAP kinase pathway and its interaction with p38 decreases during cellular stress. STK39 acts as an intermediate in the response to cellular stress. STK39 is also an independent risk factor for hypertension in men and its intragenic SNPs can interact and function in the control of blood pressure.

Specifications

• Antigen: SPAK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: STK39
• Gene Alias: AW227544; AW556857; DCHT; DKFZp686K05124; kidney-specific SPAK; pancreatic serine/threonine-protein kinase; Pask; proline-alanine-rich STE20-related kinase; PS/TK; PSTK1; RF005; Rnl5; serine threonine kinase 39; serine threonine kinase 39 (STE20/SPS1 homolog, yeast); serine/threonine kinase 39; serine/threonine kinase 39, STE20/SPS1 homolog; serine/threonine-protein kinase 39; small intestine SPAK-like kinase; Spak; Ste-20 related kinase; STE20/SPS1 homolog; STE20/SPS1-related proline-alanine-rich protein kinase; Ste20-like protein kinase; ste-20-related kinase; Stk39
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27347, 53416, 54348
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O88506, Q9UEW8, Q9Z1W9
• Gene Symbols: STK39
• Immunogen: A synthesized peptide derived from human STK39(Accession Q9UEW8), corresponding to amino acid residues D381-V431.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG