Invitrogen™ SPA17 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA558013

Product Code. 15775901

Description

Immunogen sequence: EQPDNIPAFA AAYFESLLEK REKTNFDPAE WGSKVEDRFY NNHAFEEQEP PEKSDPKQEE SQISGKEEET SVTILDSSEE DKEKEEVAAV K Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 67%.

This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.

Specifications

• Antigen: SPA17
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPA17
• Gene Alias: band 34; cancer/testis antigen 22; CT22; SP17; SP17 protein; SP17-1; SPA17; Sperm autoantigenic protein 17; sperm protein 17; Sperm surface protein Sp17; Unknown (protein for MGC:127855); zgc:153721
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 53340
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q15506
• Gene Symbols: SPA17
• Immunogen: Recombinant protein corresponding to Human SPA17. Recombinant protein control fragment (Product #RP-97273).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG