Invitrogen™ SP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5116553

Product Code. 17249053

Description

Positive Samples: A-549, PC-3, Mouse liver, Mouse brain, Rat testis Immunogen sequence: NKKGIHSSST VLASVEAARD DTLITAGGTT LILANIQQGS VSGIGTVNTS ATSNQDILTN TEIPLQLVTV SGNETME.

This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.

Specifications

• Antigen: SP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SP3
• Gene Alias: D130027J01Rik; DKFZp686O1631; GC-binding transcription factor Sp3; SP3; Sp3 transcription factor; specificity protein 3; SPR1; SPR-1; SPR2; SPR-2; trans-acting transcription factor 3; transcription factor Sp3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20687, 367846, 6670
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.12 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O70494, Q02447
• Gene Symbols: SP3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 705-781 of human SP3 (NP_0031021).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG