Invitrogen™ Sp17 Polyclonal Antibody

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
17750834	Invitrogen™ PA5119430	200 μL
17722984	Invitrogen™ PA5121584	20 μL

Description

Sp17 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.

Specifications

• Antigen: Sp17
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Mouse, Rat
• Gene: SPA17
• Gene Alias: band 34; cancer/testis antigen 22; CT22; SP17; SP17 protein; SP17-1; SPA17; Sperm autoantigenic protein 17; sperm protein 17; Sperm surface protein Sp17; Unknown (protein for MGC:127855); zgc:153721
• Gene Symbols: SPA17
• Primary or Secondary: Primary
• Purification Method: Antigen affinity chromatography, Protein A

• Concentration: 0.5 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: Q62252
• Gene ID (Entrez): 20686, 85244
• Immunogen: Recombinant protein Sperm Protein 17. The antigen corresponds to amino acid range 1-149 of the target protein.
• Product Type: Antibody