SP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 21962-1-AP-20UL

Product Code. 16891505

Description

SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.

Specifications

• Antigen: SP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SP1
• Gene Alias: SP1, Sp1 transcription factor, Transcription factor Sp1, TSFP1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20683, 24790, 6667
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunoprecipitation, Immunofluorescence
• Concentration: 0.2 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O89090, P08047, Q01714
• Gene Symbols: SP1
• Immunogen: SP1 Fusion Protein Ag16720
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Rat, Mouse, Human
• Product Type: Antibody
• Isotype: IgG