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Invitrogen™ SP1 Polyclonal Antibody

Product Code. 16343485
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Quantity:
100 μL
Unit Size:
100µL
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16343485 100 μL 100µL
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Product Code. 16343485 Supplier Invitrogen™ Supplier No. PA586610

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Description

Rabbit Polyclonal Antibody

Purity is > 95% by SDS-PAGE.

SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SP1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene SP1
Gene Accession No. O89090, P08047, Q01714
Gene Alias 1110003E12Rik; AA450830; AI845540; HGNC:11205; SP1; Sp1 transcription factor; Sp1-1; specificity protein 1; trans-acting transcription factor 1; transcription factor Sp1; TSFP1
Gene Symbols SP1
Host Species Rabbit
Immunogen Synthetic peptide, corresponding to amino acids 311-360 of Human Sp1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20683, 24790, 6667
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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