SP-D Antibody (1.7), DyLight 488, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP1-41050G

Product Code. 18246413

Description

SP-D Monoclonal specifically detects SP-D in Mouse, Porcine samples. It is validated for Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Specifications

• Antigen: SP-D
• Classification: Monoclonal
• Conjugate: DyLight 488
• Gene Alias: COLEC7collectin-7, collectin 7, Collectin-7, Lung surfactant protein D, PSPD, PSP-D, SFTP4pulmonary surfactant-associated protein D, SP-Dpulmonary surfactant apoprotein, surfactant protein D, surfactant, pulmonary-associated protein D, surfactant-associated protein, pulmonary 4
• Host Species: Mouse
• Purification Method: Protein G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This antibody detects porcine surfactant protein D (pSP-D), a 138kD member of the collectin family of proteins. Surfactant protein D is thought to play a significant role in the innate immune response against microorganisms within the lungs and at other mucosal surfaces. SP-D is a multifunctional protein which binds selectively to saccharides and lipids on microbial surfaces promoting antimicrobial responses and regulating surfactant lipid homeostasis. SP-D expression is induced in lung surfactant in response to aerogenous bacterial infection, and upon binding to bacteria, promotes phagocytosis and antigen presentation by dendritic cells. Recent studies suggest that pSP-D could serve as a serum biomarker specific for bronchopneumonia in pigs.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1

• Applications: Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: 1.7
• Dilution: Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Gene Symbols: SFTPD
• Immunogen: Purified porcine surfactant protein D
• Quantity: 0.125 mL
• Research Discipline: Cell Cycle and Replication
• Gene ID (Entrez): 6441
• Target Species: Pig
• Form: Purified

For Research Use Only