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Invitrogen™ SOX2 Polyclonal Antibody
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Product Code. 11511832
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Quantity:
100 μL
Unit Size:
100µL
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11511832 100 μL 100µL
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Product Code. 11511832 Supplier Invitrogen™ Supplier No. PA116968

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Description

Rabbit Polyclonal Antibody

The target sequence has 92% sequence homology with chicken, 86% sequence homology with xenopus, and 71% sequence homology with zebrafish. Suggested positive control: antigen standard for SOX2 (transient overexpression lysate), mouse brain lysate, mouse brain protein, uterual endometrial glands.

SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SOX2
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene SOX2
Gene Accession No. P48431, P48432, P54231
Gene Alias ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MCOPS3 (Microphthalmia Syndromic type 3); RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y) box 2; SRY (sex determining region Y)-box 2; SRY box 2; SRY related HMG box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389
Gene Symbols SOX2
Host Species Rabbit
Immunogen A synthetic peptide made to the N-terminal region of human SOX2 protein (within residues 1-100).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 101110563, 20674, 488092, 499593, 6657
Target Species Human, Mouse, Rat, Canine, Sheep
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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