Invitrogen™ SOX2 Chimeric Recombinant Mouse Monoclonal Antibody (Btjce)

Mouse Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30274830	Invitrogen™ 740013M	100 μL
30275367	Invitrogen™ 740013M20UG	20 μL

Description

This antibody has Rat Variable heavy and light chains, and Mouse constant domains. It recognizes SOX2 protein. This chimeric antibody is recognized by anti-mouse secondary antibodies. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.

Specifications

• Antigen: SOX2 Chimeric
• Concentration: 1.0 mg/mL
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Multiplex Immunohistochemistry
• Conjugate: Unconjugated
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P48431, P48432
• Gene ID (Entrez): 20674, 499593, 6657
• Primary or Secondary: Primary
• Purification Method: Affinity chromatography

• Clone: Btjce
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG1 κ
• Target Species: Human, Mouse, Rat
• Gene: SOX2
• Gene Alias: ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MCOPS3 (Microphthalmia Syndromic type 3); RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y) box 2; SRY (sex determining region Y)-box 2; SRY box 2; SRY related HMG box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389
• Gene Symbols: SOX2
• Product Type: Antibody