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  6. Invitrogen™ SOX1 Recombinant Rabbit Monoclonal Antibody (K01_3K17)

Invitrogen™ SOX1 Recombinant Rabbit Monoclonal Antibody (K01_3K17)

Product Code. 30829325
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30829325 100 μL
30829638 50 μL
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Product Code. 30829325 Supplier Invitrogen™ Supplier No. MA564334

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Description

Rabbit Recombinant Monoclonal Antibody

SOX1 Recombinant Monoclonal Antibody for Western Blot

SOX1, also known as SRY (sex determining region Y)-box 1, is a transcription factor belonging to the SRY-related HMG box family of transcription factors with a HMG box DNA-binding domain. SOX1 works through multiple independent pathways to promote neuronal cell fate determination and differentiation. This nuclear protein acts as a modulator of LINE retroposons promoter activity and is also involved in the development of the central nervous system, mainly neural and lens development. Transcriptional activator SOX1 binds directly to the HES1 promoter and suppresses HES1 transcription, thus attenuating Notch signaling. It also binds to beta-catenin and suppresses beta-catenin-mediated TCF/LEF signaling, thus potentially attenuating the WNT signaling pathway. Expression of SOX1 is seen mostly in embryonic tissues and moderately in brain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SOX1
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_3K17
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 40% glycerol, 0.05% BSA, 150mM NaCl and 0.01% sodium azide; pH 7.4
Gene SOX1
Gene Accession No. O00570, P53783
Gene Alias BB176347; LOC100912302; sex determining region Y-box 1; Sox1; Sox-1; sox1.S; SRY (sex determining region Y)-box 1; SRY box 1; SRY-box 1; SRY-box 1 S homeolog; SRY-box containing gene 1; SRY-box containing protein; SRY-box transcription factor 1; SRY-related HMG-box gene 1; transcription factor SOX-1; transcription factor SOX-1-like; XELAEV_18015596mg; XlSox1; xSox1
Gene Symbols SOX1
Host Species Rabbit
Immunogen Peptide.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100912302, 20664, 6656
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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