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Soraprazan, MedChemExpress

Product Code. 16492576
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Product Code. 16492576 Supplier Medchem Express Supplier No. HY100414

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Description

MedChemExpress Soraprazan (BYK61359) is a selective, reversible K-competitive inhibitor of the H,K-ATPase (Ki=6.4 nM), with an IC50 of 0.19 μM in gastric glands. Soraprazan binds to the H,K-ATPase with a Kd of 28.27 nM. Soraprazan shows immediate inhibition of acid secretion and is more than 2000-fold selective for H,K-ATPase over Na,K- and Ca-ATPases.

Soraprazan (BYK61359) is a selective, reversible K-competitive inhibitor of the H,K-ATPase (Ki=6.4 nM), with an IC50 of 0.19 μM in gastric glands. Soraprazan binds to the H,K-ATPase with a Kd of 28.27 nM. Soraprazan shows immediate inhibition of acid secretion and is more than 2000-fold selective for H,K-ATPase over Na,K- and Ca-ATPases.

Specifications

Chemical Name or Material Soraprazan
CAS 261944-46-1
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C21H25N3O3
Quantity 25 mg
Synonym BYK61359
Solubility Information DMSO : ≥ 150 mg/mL (408.23 mM)
SMILES O[C@@H]1[C@@H](C2=CC=CC=C2)NC3=C(C=CN4C3=NC(C)=C4C)[C@H]1OCCOC
Molecular Weight (g/mol) 367.44
Formula Weight 367.44
Percent Purity 99.69%
Grade Research
Physical Form Solid
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