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STEMCELL Technologies Sodium Butyrate

Product Code. 17180042
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Quantity:
500 mg
Unit Size:
500mg
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Product Code. 17180042 Supplier STEMCELL Technologies Supplier No. 72242

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Description

Epigenetic modifier; Inhibits histone deacetylase

  • Sodium Butyrate is the sodium salt of butyric acid, a short chain fatty acid that inhibits histone deacetylases (HDACs), leading to hyperacetylation of histones
  • This causes changes in chromatin structure and gene expression, resulting in many biological effects
  • (Boffa et al.; Kruh)
  • Promotes reprogramming of human somatic cells to induced pluripotent stem (iPS) cells using only a single factor, OCT4 (Zhu et al.)
  • Supports self-renewal of mouse and human embryonic stem (ES) cells, in the absence of exogenously added growth factors (Ware et al.)
  • Promotes differentiation to hepatocytes from mouse and human ES cells (Hay et al.; Zhou et al.)
  • Promotes differentiation to definitive endoderm and islet-like cells from human ES cells (Jiang et al.)
  • Enhances osteogenic and suppresses adipogenic differentiation from human mesenchymal cells (Chen et al.; Lee et al.)

Specifications

CAS 156-54-7
Synonym Butanoic acid; Butyric acid, sodium salt
Quantity 500 mg
Molecular Formula C4H7O2 · Na
Purity ≥95%
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