Invitrogen™ SOCS7 Recombinant Rabbit Monoclonal Antibody (24GB1820)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30275633	Invitrogen™ MA557271	100 μL
30275639	Invitrogen™ MA557272	20 μL

Description

SOCS7 Recombinant Monoclonal Antibody for Western Blot, Flow

SOCS7 regulates signaling cascades probably through protein ubiquitination and/or sequestration. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. SOCS7 may be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Specifications

• Antigen: SOCS7
• Concentration: 0.2 mg/mL
• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O14512, Q8VHQ2
• Gene ID (Entrez): 192157, 287659, 30837
• Immunogen: A synthesized peptide derived from human SOCS7 (aa 1-50).
• Product Type: Antibody

• Clone: 24GB1820
• Content And Storage: -20°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Mouse, Rat
• Gene: SOCS7
• Gene Alias: 2310063P06Rik; C85125; Cish7; NAP4; NAP-4; Nck, Ash and phospholipase C binding protein; nck, Ash and phospholipase C gamma-binding protein; NCKAP4; Nck-associated protein 4; SH2 domain containing SOCS box protein SOCS7; SOCS6; SOCS7; SOCS-7; suppressor of cytokine signaling 6; suppressor of cytokine signaling 7
• Gene Symbols: SOCS7
• Primary or Secondary: Primary
• Purification Method: Affinity chromatography