Invitrogen™ SOCS2 Recombinant Rabbit Monoclonal Antibody (6D3F6)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA535776

Product Code. 17156433

Description

Immunogen sequence: MTLRCLEPSG NGGEGTRSQW GTAGSAEEPS PQAARLAKAL RELGQTGWYW GSMTVNEAKE KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ DGKFRLDSII CVKSKLKQFD SVVHLIDYYV QMCKDKRTGP EAPRNGTVHL YLTKPLYTSA PSLQHLCRLT INKCTGAIWG LPLPTRLKDY LEEYKFQV.

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control.

Specifications

• Antigen: SOCS2
• Classification: Recombinant Monoclonal
• Concentration: 2.0 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O14508, O35717, O88582
• Gene Symbols: SOCS2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human SOCS2 (NP_001257400.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 6D3F6
• Conjugate: Unconjugated
• Gene: SOCS2
• Gene Alias: 8030460M17; AI527257; AW108012; CIS2; CIS-2; Cish2; cytokine inducible SH2-containing protein 2; cytokine-inducible SH2 protein 2; D130043N08Rik; hg; JAB; Socs2; SOCS-2; SSI2; SSI-2; STAT induced STAT inhibitor-2; STATI2; STAT-induced STAT inhibitor 2; STAT-induced STAT inhibitor-2; Suppressor of cytokine signaling 2; suppressor of cytokine signaling-2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 216233, 84607, 8835
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid